00001 00012 #ifndef _NIFTI_HEADER_ 00013 #define _NIFTI_HEADER_ 00014 00015 /***************************************************************************** 00016 ** This file defines the "NIFTI-1" header format. ** 00017 ** It is derived from 2 meetings at the NIH (31 Mar 2003 and ** 00018 ** 02 Sep 2003) of the Data Format Working Group (DFWG), ** 00019 ** chartered by the NIfTI (Neuroimaging Informatics Technology ** 00020 ** Initiative) at the National Institutes of Health (NIH). ** 00021 **--------------------------------------------------------------** 00022 ** Neither the National Institutes of Health (NIH), the DFWG, ** 00023 ** nor any of the members or employees of these institutions ** 00024 ** imply any warranty of usefulness of this material for any ** 00025 ** purpose, and do not assume any liability for damages, ** 00026 ** incidental or otherwise, caused by any use of this document. ** 00027 ** If these conditions are not acceptable, do not use this! ** 00028 **--------------------------------------------------------------** 00029 ** Author: Robert W Cox (NIMH, Bethesda) ** 00030 ** Advisors: John Ashburner (FIL, London), ** 00031 ** Stephen Smith (FMRIB, Oxford), ** 00032 ** Mark Jenkinson (FMRIB, Oxford) ** 00033 ******************************************************************************/ 00034 00035 /*---------------------------------------------------------------------------*/ 00036 /* Note that the ANALYZE 7.5 file header (dbh.h) is 00037 (c) Copyright 1986-1995 00038 Biomedical Imaging Resource 00039 Mayo Foundation 00040 Incorporation of components of dbh.h are by permission of the 00041 Mayo Foundation. 00042 00043 Changes from the ANALYZE 7.5 file header in this file are released to the 00044 public domain, including the functional comments and any amusing asides. 00045 -----------------------------------------------------------------------------*/ 00046 00047 /*---------------------------------------------------------------------------*/ 00115 /*---------------------------------------------------------------------------*/ 00116 /* HEADER STRUCT DECLARATION: 00117 ------------------------- 00118 In the comments below for each field, only NIFTI-1 specific requirements 00119 or changes from the ANALYZE 7.5 format are described. For convenience, 00120 the 348 byte header is described as a single struct, rather than as the 00121 ANALYZE 7.5 group of 3 substructs. 00122 00123 Further comments about the interpretation of various elements of this 00124 header are after the data type definition itself. Fields that are 00125 marked as ++UNUSED++ have no particular interpretation in this standard. 00126 (Also see the UNUSED FIELDS comment section, far below.) 00127 00128 The presumption below is that the various C types have particular sizes: 00129 sizeof(int) = sizeof(float) = 4 ; sizeof(short) = 2 00130 -----------------------------------------------------------------------------*/ 00131 00132 /*=================*/ 00133 #ifdef __cplusplus 00134 extern "C" { 00135 #endif 00136 /*=================*/ 00137 00143 /*************************/ /************************/ 00144 struct nifti_1_header { /* NIFTI-1 usage */ /* ANALYZE 7.5 field(s) */ 00145 /*************************/ /************************/ 00146 00147 /*--- was header_key substruct ---*/ 00148 int sizeof_hdr; /* int sizeof_hdr; */ 00149 char data_type[10]; /* char data_type[10]; */ 00150 char db_name[18]; /* char db_name[18]; */ 00151 int extents; /* int extents; */ 00152 short session_error; /* short session_error; */ 00153 char regular; /* char regular; */ 00154 char dim_info; /* char hkey_un0; */ 00155 00156 /*--- was image_dimension substruct ---*/ 00157 short dim[8]; /* short dim[8]; */ 00158 float intent_p1 ; /* short unused8; */ 00159 /* short unused9; */ 00160 float intent_p2 ; /* short unused10; */ 00161 /* short unused11; */ 00162 float intent_p3 ; /* short unused12; */ 00163 /* short unused13; */ 00164 short intent_code ; /* short unused14; */ 00165 short datatype; /* short datatype; */ 00166 short bitpix; /* short bitpix; */ 00167 short slice_start; /* short dim_un0; */ 00168 float pixdim[8]; /* float pixdim[8]; */ 00169 float vox_offset; /* float vox_offset; */ 00170 float scl_slope ; /* float funused1; */ 00171 float scl_inter ; /* float funused2; */ 00172 short slice_end; /* float funused3; */ 00173 char slice_code ; 00174 char xyzt_units ; 00175 float cal_max; /* float cal_max; */ 00176 float cal_min; /* float cal_min; */ 00177 float slice_duration; /* float compressed; */ 00178 float toffset; /* float verified; */ 00179 int glmax; /* int glmax; */ 00180 int glmin; /* int glmin; */ 00181 00182 /*--- was data_history substruct ---*/ 00183 char descrip[80]; /* char descrip[80]; */ 00184 char aux_file[24]; /* char aux_file[24]; */ 00185 00186 short qform_code ; /*-- all ANALYZE 7.5 ---*/ 00187 short sform_code ; /* fields below here */ 00188 /* are replaced */ 00189 float quatern_b ; 00190 float quatern_c ; 00191 float quatern_d ; 00192 float qoffset_x ; 00193 float qoffset_y ; 00194 float qoffset_z ; 00196 float srow_x[4] ; 00197 float srow_y[4] ; 00198 float srow_z[4] ; 00200 char intent_name[16]; 00202 char magic[4] ; 00204 } ; /**** 348 bytes total ****/ 00205 00206 typedef struct nifti_1_header nifti_1_header ; 00207 00208 /*---------------------------------------------------------------------------*/ 00209 /* HEADER EXTENSIONS: 00210 ----------------- 00211 After the end of the 348 byte header (e.g., after the magic field), 00212 the next 4 bytes are a char array field named "extension". By default, 00213 all 4 bytes of this array should be set to zero. In a .nii file, these 00214 4 bytes will always be present, since the earliest start point for 00215 the image data is byte #352. In a separate .hdr file, these bytes may 00216 or may not be present. If not present (i.e., if the length of the .hdr 00217 file is 348 bytes), then a NIfTI-1 compliant program should use the 00218 default value of extension={0,0,0,0}. The first byte (extension[0]) 00219 is the only value of this array that is specified at present. The other 00220 3 bytes are reserved for future use. 00221 00222 If extension[0] is nonzero, it indicates that extended header information 00223 is present in the bytes following the extension array. In a .nii file, 00224 this extended header data is before the image data (and vox_offset 00225 must be set correctly to allow for this). In a .hdr file, this extended 00226 data follows extension and proceeds (potentially) to the end of the file. 00227 00228 The format of extended header data is weakly specified. Each extension 00229 must be an integer multiple of 16 bytes long. The first 8 bytes of each 00230 extension comprise 2 integers: 00231 int esize , ecode ; 00232 These values may need to be byte-swapped, as indicated by dim[0] for 00233 the rest of the header. 00234 * esize is the number of bytes that form the extended header data 00235 + esize must be a positive integral multiple of 16 00236 + this length includes the 8 bytes of esize and ecode themselves 00237 * ecode is a non-negative integer that indicates the format of the 00238 extended header data that follows 00239 + different ecode values are assigned to different developer groups 00240 + at present, the "registered" values for code are 00241 = 0 = unknown private format (not recommended!) 00242 = 2 = DICOM format (i.e., attribute tags and values) 00243 = 4 = AFNI group (i.e., ASCII XML-ish elements) 00244 In the interests of interoperability (a primary rationale for NIfTI), 00245 groups developing software that uses this extension mechanism are 00246 encouraged to document and publicize the format of their extensions. 00247 To this end, the NIfTI DFWG will assign even numbered codes upon request 00248 to groups submitting at least rudimentary documentation for the format 00249 of their extension; at present, the contact is mailto:rwcox@nih.gov. 00250 The assigned codes and documentation will be posted on the NIfTI 00251 website. All odd values of ecode (and 0) will remain unassigned; 00252 at least, until the even ones are used up, when we get to 2,147,483,646. 00253 00254 Note that the other contents of the extended header data section are 00255 totally unspecified by the NIfTI-1 standard. In particular, if binary 00256 data is stored in such a section, its byte order is not necessarily 00257 the same as that given by examining dim[0]; it is incumbent on the 00258 programs dealing with such data to determine the byte order of binary 00259 extended header data. 00260 00261 Multiple extended header sections are allowed, each starting with an 00262 esize,ecode value pair. The first esize value, as described above, 00263 is at bytes #352-355 in the .hdr or .nii file (files start at byte #0). 00264 If this value is positive, then the second (esize2) will be found 00265 starting at byte #352+esize1 , the third (esize3) at byte #352+esize1+esize2, 00266 et cetera. Of course, in a .nii file, the value of vox_offset must 00267 be compatible with these extensions. If a malformed file indicates 00268 that an extended header data section would run past vox_offset, then 00269 the entire extended header section should be ignored. In a .hdr file, 00270 if an extended header data section would run past the end-of-file, 00271 that extended header data should also be ignored. 00272 00273 With the above scheme, a program can successively examine the esize 00274 and ecode values, and skip over each extended header section if the 00275 program doesn't know how to interpret the data within. Of course, any 00276 program can simply ignore all extended header sections simply by jumping 00277 straight to the image data using vox_offset. 00278 -----------------------------------------------------------------------------*/ 00279 00287 struct nifti1_extender { char extension[4] ; } ; 00288 typedef struct nifti1_extender nifti1_extender ; 00289 00293 struct nifti1_extension { 00294 int esize ; 00295 int ecode ; 00296 char * edata ; 00297 } ; 00298 typedef struct nifti1_extension nifti1_extension ; 00299 00300 /*---------------------------------------------------------------------------*/ 00301 /* DATA DIMENSIONALITY (as in ANALYZE 7.5): 00302 --------------------------------------- 00303 dim[0] = number of dimensions; 00304 - if dim[0] is outside range 1..7, then the header information 00305 needs to be byte swapped appropriately 00306 - ANALYZE supports dim[0] up to 7, but NIFTI-1 reserves 00307 dimensions 1,2,3 for space (x,y,z), 4 for time (t), and 00308 5,6,7 for anything else needed. 00309 00310 dim[i] = length of dimension #i, for i=1..dim[0] (must be positive) 00311 - also see the discussion of intent_code, far below 00312 00313 pixdim[i] = voxel width along dimension #i, i=1..dim[0] (positive) 00314 - cf. ORIENTATION section below for use of pixdim[0] 00315 - the units of pixdim can be specified with the xyzt_units 00316 field (also described far below). 00317 00318 Number of bits per voxel value is in bitpix, which MUST correspond with 00319 the datatype field. The total number of bytes in the image data is 00320 dim[1] * ... * dim[dim[0]] * bitpix / 8 00321 00322 In NIFTI-1 files, dimensions 1,2,3 are for space, dimension 4 is for time, 00323 and dimension 5 is for storing multiple values at each spatiotemporal 00324 voxel. Some examples: 00325 - A typical whole-brain FMRI experiment's time series: 00326 - dim[0] = 4 00327 - dim[1] = 64 pixdim[1] = 3.75 xyzt_units = NIFTI_UNITS_MM 00328 - dim[2] = 64 pixdim[2] = 3.75 | NIFTI_UNITS_SEC 00329 - dim[3] = 20 pixdim[3] = 5.0 00330 - dim[4] = 120 pixdim[4] = 2.0 00331 - A typical T1-weighted anatomical volume: 00332 - dim[0] = 3 00333 - dim[1] = 256 pixdim[1] = 1.0 xyzt_units = NIFTI_UNITS_MM 00334 - dim[2] = 256 pixdim[2] = 1.0 00335 - dim[3] = 128 pixdim[3] = 1.1 00336 - A single slice EPI time series: 00337 - dim[0] = 4 00338 - dim[1] = 64 pixdim[1] = 3.75 xyzt_units = NIFTI_UNITS_MM 00339 - dim[2] = 64 pixdim[2] = 3.75 | NIFTI_UNITS_SEC 00340 - dim[3] = 1 pixdim[3] = 5.0 00341 - dim[4] = 1200 pixdim[4] = 0.2 00342 - A 3-vector stored at each point in a 3D volume: 00343 - dim[0] = 5 00344 - dim[1] = 256 pixdim[1] = 1.0 xyzt_units = NIFTI_UNITS_MM 00345 - dim[2] = 256 pixdim[2] = 1.0 00346 - dim[3] = 128 pixdim[3] = 1.1 00347 - dim[4] = 1 pixdim[4] = 0.0 00348 - dim[5] = 3 intent_code = NIFTI_INTENT_VECTOR 00349 - A single time series with a 3x3 matrix at each point: 00350 - dim[0] = 5 00351 - dim[1] = 1 xyzt_units = NIFTI_UNITS_SEC 00352 - dim[2] = 1 00353 - dim[3] = 1 00354 - dim[4] = 1200 pixdim[4] = 0.2 00355 - dim[5] = 9 intent_code = NIFTI_INTENT_GENMATRIX 00356 - intent_p1 = intent_p2 = 3.0 (indicates matrix dimensions) 00357 -----------------------------------------------------------------------------*/ 00358 00359 /*---------------------------------------------------------------------------*/ 00360 /* DATA STORAGE: 00361 ------------ 00362 If the magic field is "n+1", then the voxel data is stored in the 00363 same file as the header. In this case, the voxel data starts at offset 00364 (int)vox_offset into the header file. Thus, vox_offset=352.0 means that 00365 the data starts immediately after the NIFTI-1 header. If vox_offset is 00366 greater than 352, the NIFTI-1 format does not say much about the 00367 contents of the dataset file between the end of the header and the 00368 start of the data. 00369 00370 FILES: 00371 ----- 00372 If the magic field is "ni1", then the voxel data is stored in the 00373 associated ".img" file, starting at offset 0 (i.e., vox_offset is not 00374 used in this case, and should be set to 0.0). 00375 00376 When storing NIFTI-1 datasets in pairs of files, it is customary to name 00377 the files in the pattern "name.hdr" and "name.img", as in ANALYZE 7.5. 00378 When storing in a single file ("n+1"), the file name should be in 00379 the form "name.nii" (the ".nft" and ".nif" suffixes are already taken; 00380 cf. http://www.icdatamaster.com/n.html ). 00381 00382 BYTE ORDERING: 00383 ------------- 00384 The byte order of the data arrays is presumed to be the same as the byte 00385 order of the header (which is determined by examining dim[0]). 00386 00387 Floating point types are presumed to be stored in IEEE-754 format. 00388 -----------------------------------------------------------------------------*/ 00389 00390 /*---------------------------------------------------------------------------*/ 00391 /* DETAILS ABOUT vox_offset: 00392 ------------------------ 00393 In a .nii file, the vox_offset field value is interpreted as the start 00394 location of the image data bytes in that file. In a .hdr/.img file pair, 00395 the vox_offset field value is the start location of the image data 00396 bytes in the .img file. 00397 * If vox_offset is less than 352 in a .nii file, it is equivalent 00398 to 352 (i.e., image data never starts before byte #352 in a .nii file). 00399 * The default value for vox_offset in a .nii file is 352. 00400 * In a .hdr file, the default value for vox_offset is 0. 00401 * vox_offset should be an integer multiple of 16; otherwise, some 00402 programs may not work properly (e.g., SPM). This is to allow 00403 memory-mapped input to be properly byte-aligned. 00404 Note that since vox_offset is an IEEE-754 32 bit float (for compatibility 00405 with the ANALYZE-7.5 format), it effectively has a 24 bit mantissa. All 00406 integers from 0 to 2^24 can be represented exactly in this format, but not 00407 all larger integers are exactly storable as IEEE-754 32 bit floats. However, 00408 unless you plan to have vox_offset be potentially larger than 16 MB, this 00409 should not be an issue. (Actually, any integral multiple of 16 up to 2^27 00410 can be represented exactly in this format, which allows for up to 128 MB 00411 of random information before the image data. If that isn't enough, then 00412 perhaps this format isn't right for you.) 00413 00414 In a .img file (i.e., image data stored separately from the NIfTI-1 00415 header), data bytes between #0 and #vox_offset-1 (inclusive) are completely 00416 undefined and unregulated by the NIfTI-1 standard. One potential use of 00417 having vox_offset > 0 in the .hdr/.img file pair storage method is to make 00418 the .img file be a copy of (or link to) a pre-existing image file in some 00419 other format, such as DICOM; then vox_offset would be set to the offset of 00420 the image data in this file. (It may not be possible to follow the 00421 "multiple-of-16 rule" with an arbitrary external file; using the NIfTI-1 00422 format in such a case may lead to a file that is incompatible with software 00423 that relies on vox_offset being a multiple of 16.) 00424 00425 In a .nii file, data bytes between #348 and #vox_offset-1 (inclusive) may 00426 be used to store user-defined extra information; similarly, in a .hdr file, 00427 any data bytes after byte #347 are available for user-defined extra 00428 information. The (very weak) regulation of this extra header data is 00429 described elsewhere. 00430 -----------------------------------------------------------------------------*/ 00431 00432 /*---------------------------------------------------------------------------*/ 00433 /* DATA SCALING: 00434 ------------ 00435 If the scl_slope field is nonzero, then each voxel value in the dataset 00436 should be scaled as 00437 y = scl_slope * x + scl_inter 00438 where x = voxel value stored 00439 y = "true" voxel value 00440 Normally, we would expect this scaling to be used to store "true" floating 00441 values in a smaller integer datatype, but that is not required. That is, 00442 it is legal to use scaling even if the datatype is a float type (crazy, 00443 perhaps, but legal). 00444 - However, the scaling is to be ignored if datatype is DT_RGB24. 00445 - If datatype is a complex type, then the scaling is to be 00446 applied to both the real and imaginary parts. 00447 00448 The cal_min and cal_max fields (if nonzero) are used for mapping (possibly 00449 scaled) dataset values to display colors: 00450 - Minimum display intensity (black) corresponds to dataset value cal_min. 00451 - Maximum display intensity (white) corresponds to dataset value cal_max. 00452 - Dataset values below cal_min should display as black also, and values 00453 above cal_max as white. 00454 - Colors "black" and "white", of course, may refer to any scalar display 00455 scheme (e.g., a color lookup table specified via aux_file). 00456 - cal_min and cal_max only make sense when applied to scalar-valued 00457 datasets (i.e., dim[0] < 5 or dim[5] = 1). 00458 -----------------------------------------------------------------------------*/ 00459 00460 /*---------------------------------------------------------------------------*/ 00461 /* TYPE OF DATA (acceptable values for datatype field): 00462 --------------------------------------------------- 00463 Values of datatype smaller than 256 are ANALYZE 7.5 compatible. 00464 Larger values are NIFTI-1 additions. These are all multiples of 256, so 00465 that no bits below position 8 are set in datatype. But there is no need 00466 to use only powers-of-2, as the original ANALYZE 7.5 datatype codes do. 00467 00468 The additional codes are intended to include a complete list of basic 00469 scalar types, including signed and unsigned integers from 8 to 64 bits, 00470 floats from 32 to 128 bits, and complex (float pairs) from 64 to 256 bits. 00471 00472 Note that most programs will support only a few of these datatypes! 00473 A NIFTI-1 program should fail gracefully (e.g., print a warning message) 00474 when it encounters a dataset with a type it doesn't like. 00475 -----------------------------------------------------------------------------*/ 00476 00477 #undef DT_UNKNOWN /* defined in dirent.h on some Unix systems */ 00478 00483 /*--- the original ANALYZE 7.5 type codes ---*/ 00484 #define DT_NONE 0 00485 #define DT_UNKNOWN 0 /* what it says, dude */ 00486 #define DT_BINARY 1 /* binary (1 bit/voxel) */ 00487 #define DT_UNSIGNED_CHAR 2 /* unsigned char (8 bits/voxel) */ 00488 #define DT_SIGNED_SHORT 4 /* signed short (16 bits/voxel) */ 00489 #define DT_SIGNED_INT 8 /* signed int (32 bits/voxel) */ 00490 #define DT_FLOAT 16 /* float (32 bits/voxel) */ 00491 #define DT_COMPLEX 32 /* complex (64 bits/voxel) */ 00492 #define DT_DOUBLE 64 /* double (64 bits/voxel) */ 00493 #define DT_RGB 128 /* RGB triple (24 bits/voxel) */ 00494 #define DT_ALL 255 /* not very useful (?) */ 00495 00496 /*----- another set of names for the same ---*/ 00497 #define DT_UINT8 2 00498 #define DT_INT16 4 00499 #define DT_INT32 8 00500 #define DT_FLOAT32 16 00501 #define DT_COMPLEX64 32 00502 #define DT_FLOAT64 64 00503 #define DT_RGB24 128 00504 00505 /*------------------- new codes for NIFTI ---*/ 00506 #define DT_INT8 256 /* signed char (8 bits) */ 00507 #define DT_UINT16 512 /* unsigned short (16 bits) */ 00508 #define DT_UINT32 768 /* unsigned int (32 bits) */ 00509 #define DT_INT64 1024 /* long long (64 bits) */ 00510 #define DT_UINT64 1280 /* unsigned long long (64 bits) */ 00511 #define DT_FLOAT128 1536 /* long double (128 bits) */ 00512 #define DT_COMPLEX128 1792 /* double pair (128 bits) */ 00513 #define DT_COMPLEX256 2048 /* long double pair (256 bits) */ 00514 #define DT_RGBA32 2304 /* 4 byte RGBA (32 bits/voxel) */ 00515 /* @} */ 00516 00517 00518 /*------- aliases for all the above codes ---*/ 00519 00525 #define NIFTI_TYPE_UINT8 2 00526 00527 #define NIFTI_TYPE_INT16 4 00528 00529 #define NIFTI_TYPE_INT32 8 00530 00531 #define NIFTI_TYPE_FLOAT32 16 00532 00533 #define NIFTI_TYPE_COMPLEX64 32 00534 00535 #define NIFTI_TYPE_FLOAT64 64 00536 00537 #define NIFTI_TYPE_RGB24 128 00538 00539 #define NIFTI_TYPE_INT8 256 00540 00541 #define NIFTI_TYPE_UINT16 512 00542 00543 #define NIFTI_TYPE_UINT32 768 00544 00545 #define NIFTI_TYPE_INT64 1024 00546 00547 #define NIFTI_TYPE_UINT64 1280 00548 00549 #define NIFTI_TYPE_FLOAT128 1536 00550 00551 #define NIFTI_TYPE_COMPLEX128 1792 00552 00553 #define NIFTI_TYPE_COMPLEX256 2048 00554 00555 #define NIFTI_TYPE_RGBA32 2304 00556 /* @} */ 00557 00558 /*-------- sample typedefs for complicated types ---*/ 00559 #if 0 00560 typedef struct { float r,i; } complex_float ; 00561 typedef struct { double r,i; } complex_double ; 00562 typedef struct { long double r,i; } complex_longdouble ; 00563 typedef struct { unsigned char r,g,b; } rgb_byte ; 00564 #endif 00565 00566 /*---------------------------------------------------------------------------*/ 00567 /* INTERPRETATION OF VOXEL DATA: 00568 ---------------------------- 00569 The intent_code field can be used to indicate that the voxel data has 00570 some particular meaning. In particular, a large number of codes is 00571 given to indicate that the the voxel data should be interpreted as 00572 being drawn from a given probability distribution. 00573 00574 VECTOR-VALUED DATASETS: 00575 ---------------------- 00576 The 5th dimension of the dataset, if present (i.e., dim[0]=5 and 00577 dim[5] > 1), contains multiple values (e.g., a vector) to be stored 00578 at each spatiotemporal location. For example, the header values 00579 - dim[0] = 5 00580 - dim[1] = 64 00581 - dim[2] = 64 00582 - dim[3] = 20 00583 - dim[4] = 1 (indicates no time axis) 00584 - dim[5] = 3 00585 - datatype = DT_FLOAT 00586 - intent_code = NIFTI_INTENT_VECTOR 00587 mean that this dataset should be interpreted as a 3D volume (64x64x20), 00588 with a 3-vector of floats defined at each point in the 3D grid. 00589 00590 A program reading a dataset with a 5th dimension may want to reformat 00591 the image data to store each voxels' set of values together in a struct 00592 or array. This programming detail, however, is beyond the scope of the 00593 NIFTI-1 file specification! Uses of dimensions 6 and 7 are also not 00594 specified here. 00595 00596 STATISTICAL PARAMETRIC DATASETS (i.e., SPMs): 00597 -------------------------------------------- 00598 Values of intent_code from NIFTI_FIRST_STATCODE to NIFTI_LAST_STATCODE 00599 (inclusive) indicate that the numbers in the dataset should be interpreted 00600 as being drawn from a given distribution. Most such distributions have 00601 auxiliary parameters (e.g., NIFTI_INTENT_TTEST has 1 DOF parameter). 00602 00603 If the dataset DOES NOT have a 5th dimension, then the auxiliary parameters 00604 are the same for each voxel, and are given in header fields intent_p1, 00605 intent_p2, and intent_p3. 00606 00607 If the dataset DOES have a 5th dimension, then the auxiliary parameters 00608 are different for each voxel. For example, the header values 00609 - dim[0] = 5 00610 - dim[1] = 128 00611 - dim[2] = 128 00612 - dim[3] = 1 (indicates a single slice) 00613 - dim[4] = 1 (indicates no time axis) 00614 - dim[5] = 2 00615 - datatype = DT_FLOAT 00616 - intent_code = NIFTI_INTENT_TTEST 00617 mean that this is a 2D dataset (128x128) of t-statistics, with the 00618 t-statistic being in the first "plane" of data and the degrees-of-freedom 00619 parameter being in the second "plane" of data. 00620 00621 If the dataset 5th dimension is used to store the voxel-wise statistical 00622 parameters, then dim[5] must be 1 plus the number of parameters required 00623 by that distribution (e.g., intent_code=NIFTI_INTENT_TTEST implies dim[5] 00624 must be 2, as in the example just above). 00625 00626 Note: intent_code values 2..10 are compatible with AFNI 1.5x (which is 00627 why there is no code with value=1, which is obsolescent in AFNI). 00628 00629 OTHER INTENTIONS: 00630 ---------------- 00631 The purpose of the intent_* fields is to help interpret the values 00632 stored in the dataset. Some non-statistical values for intent_code 00633 and conventions are provided for storing other complex data types. 00634 00635 The intent_name field provides space for a 15 character (plus 0 byte) 00636 'name' string for the type of data stored. Examples: 00637 - intent_code = NIFTI_INTENT_ESTIMATE; intent_name = "T1"; 00638 could be used to signify that the voxel values are estimates of the 00639 NMR parameter T1. 00640 - intent_code = NIFTI_INTENT_TTEST; intent_name = "House"; 00641 could be used to signify that the voxel values are t-statistics 00642 for the significance of 'activation' response to a House stimulus. 00643 - intent_code = NIFTI_INTENT_DISPVECT; intent_name = "ToMNI152"; 00644 could be used to signify that the voxel values are a displacement 00645 vector that transforms each voxel (x,y,z) location to the 00646 corresponding location in the MNI152 standard brain. 00647 - intent_code = NIFTI_INTENT_SYMMATRIX; intent_name = "DTI"; 00648 could be used to signify that the voxel values comprise a diffusion 00649 tensor image. 00650 00651 If no data name is implied or needed, intent_name[0] should be set to 0. 00652 -----------------------------------------------------------------------------*/ 00653 00656 #define NIFTI_INTENT_NONE 0 00657 00658 /*-------- These codes are for probability distributions ---------------*/ 00659 /* Most distributions have a number of parameters, 00660 below denoted by p1, p2, and p3, and stored in 00661 - intent_p1, intent_p2, intent_p3 if dataset doesn't have 5th dimension 00662 - image data array if dataset does have 5th dimension 00663 00664 Functions to compute with many of the distributions below can be found 00665 in the CDF library from U Texas. 00666 00667 Formulas for and discussions of these distributions can be found in the 00668 following books: 00669 00670 [U] Univariate Discrete Distributions, 00671 NL Johnson, S Kotz, AW Kemp. 00672 00673 [C1] Continuous Univariate Distributions, vol. 1, 00674 NL Johnson, S Kotz, N Balakrishnan. 00675 00676 [C2] Continuous Univariate Distributions, vol. 2, 00677 NL Johnson, S Kotz, N Balakrishnan. */ 00678 /*----------------------------------------------------------------------*/ 00679 00688 #define NIFTI_INTENT_CORREL 2 00689 00692 #define NIFTI_INTENT_TTEST 3 00693 00697 #define NIFTI_INTENT_FTEST 4 00698 00701 #define NIFTI_INTENT_ZSCORE 5 00702 00706 #define NIFTI_INTENT_CHISQ 6 00707 00711 #define NIFTI_INTENT_BETA 7 00712 00717 #define NIFTI_INTENT_BINOM 8 00718 00723 #define NIFTI_INTENT_GAMMA 9 00724 00728 #define NIFTI_INTENT_POISSON 10 00729 00733 #define NIFTI_INTENT_NORMAL 11 00734 00739 #define NIFTI_INTENT_FTEST_NONC 12 00740 00744 #define NIFTI_INTENT_CHISQ_NONC 13 00745 00750 #define NIFTI_INTENT_LOGISTIC 14 00751 00756 #define NIFTI_INTENT_LAPLACE 15 00757 00760 #define NIFTI_INTENT_UNIFORM 16 00761 00765 #define NIFTI_INTENT_TTEST_NONC 17 00766 00772 #define NIFTI_INTENT_WEIBULL 18 00773 00780 #define NIFTI_INTENT_CHI 19 00781 00787 #define NIFTI_INTENT_INVGAUSS 20 00788 00793 #define NIFTI_INTENT_EXTVAL 21 00794 00797 #define NIFTI_INTENT_PVAL 22 00798 00805 #define NIFTI_INTENT_LOGPVAL 23 00806 00812 #define NIFTI_INTENT_LOG10PVAL 24 00813 00816 #define NIFTI_FIRST_STATCODE 2 00817 00820 #define NIFTI_LAST_STATCODE 24 00821 00822 /*---------- these values for intent_code aren't for statistics ----------*/ 00823 00828 #define NIFTI_INTENT_ESTIMATE 1001 00829 00834 #define NIFTI_INTENT_LABEL 1002 00835 00839 #define NIFTI_INTENT_NEURONAME 1003 00840 00853 #define NIFTI_INTENT_GENMATRIX 1004 00854 00866 #define NIFTI_INTENT_SYMMATRIX 1005 00867 00875 #define NIFTI_INTENT_DISPVECT 1006 /* specifically for displacements */ 00876 #define NIFTI_INTENT_VECTOR 1007 /* for any other type of vector */ 00877 00889 #define NIFTI_INTENT_POINTSET 1008 00890 00902 #define NIFTI_INTENT_TRIANGLE 1009 00903 00911 #define NIFTI_INTENT_QUATERNION 1010 00912 00916 #define NIFTI_INTENT_DIMLESS 1011 00917 00918 /*---------- these values apply to GIFTI datasets ----------*/ 00919 00922 #define NIFTI_INTENT_TIME_SERIES 2001 00923 00927 #define NIFTI_INTENT_NODE_INDEX 2002 00928 00938 #define NIFTI_INTENT_RGB_VECTOR 2003 00939 00949 #define NIFTI_INTENT_RGBA_VECTOR 2004 00950 00954 #define NIFTI_INTENT_SHAPE 2005 00955 00956 /* @} */ 00957 00958 /*---------------------------------------------------------------------------*/ 00959 /* 3D IMAGE (VOLUME) ORIENTATION AND LOCATION IN SPACE: 00960 --------------------------------------------------- 00961 There are 3 different methods by which continuous coordinates can 00962 attached to voxels. The discussion below emphasizes 3D volumes, and 00963 the continuous coordinates are referred to as (x,y,z). The voxel 00964 index coordinates (i.e., the array indexes) are referred to as (i,j,k), 00965 with valid ranges: 00966 i = 0 .. dim[1]-1 00967 j = 0 .. dim[2]-1 (if dim[0] >= 2) 00968 k = 0 .. dim[3]-1 (if dim[0] >= 3) 00969 The (x,y,z) coordinates refer to the CENTER of a voxel. In methods 00970 2 and 3, the (x,y,z) axes refer to a subject-based coordinate system, 00971 with 00972 +x = Right +y = Anterior +z = Superior. 00973 This is a right-handed coordinate system. However, the exact direction 00974 these axes point with respect to the subject depends on qform_code 00975 (Method 2) and sform_code (Method 3). 00976 00977 N.B.: The i index varies most rapidly, j index next, k index slowest. 00978 Thus, voxel (i,j,k) is stored starting at location 00979 (i + j*dim[1] + k*dim[1]*dim[2]) * (bitpix/8) 00980 into the dataset array. 00981 00982 N.B.: The ANALYZE 7.5 coordinate system is 00983 +x = Left +y = Anterior +z = Superior 00984 which is a left-handed coordinate system. This backwardness is 00985 too difficult to tolerate, so this NIFTI-1 standard specifies the 00986 coordinate order which is most common in functional neuroimaging. 00987 00988 N.B.: The 3 methods below all give the locations of the voxel centers 00989 in the (x,y,z) coordinate system. In many cases, programs will wish 00990 to display image data on some other grid. In such a case, the program 00991 will need to convert its desired (x,y,z) values into (i,j,k) values 00992 in order to extract (or interpolate) the image data. This operation 00993 would be done with the inverse transformation to those described below. 00994 00995 N.B.: Method 2 uses a factor 'qfac' which is either -1 or 1; qfac is 00996 stored in the otherwise unused pixdim[0]. If pixdim[0]=0.0 (which 00997 should not occur), we take qfac=1. Of course, pixdim[0] is only used 00998 when reading a NIFTI-1 header, not when reading an ANALYZE 7.5 header. 00999 01000 N.B.: The units of (x,y,z) can be specified using the xyzt_units field. 01001 01002 METHOD 1 (the "old" way, used only when qform_code = 0): 01003 ------------------------------------------------------- 01004 The coordinate mapping from (i,j,k) to (x,y,z) is the ANALYZE 01005 7.5 way. This is a simple scaling relationship: 01006 01007 x = pixdim[1] * i 01008 y = pixdim[2] * j 01009 z = pixdim[3] * k 01010 01011 No particular spatial orientation is attached to these (x,y,z) 01012 coordinates. (NIFTI-1 does not have the ANALYZE 7.5 orient field, 01013 which is not general and is often not set properly.) This method 01014 is not recommended, and is present mainly for compatibility with 01015 ANALYZE 7.5 files. 01016 01017 METHOD 2 (used when qform_code > 0, which should be the "normal" case): 01018 --------------------------------------------------------------------- 01019 The (x,y,z) coordinates are given by the pixdim[] scales, a rotation 01020 matrix, and a shift. This method is intended to represent 01021 "scanner-anatomical" coordinates, which are often embedded in the 01022 image header (e.g., DICOM fields (0020,0032), (0020,0037), (0028,0030), 01023 and (0018,0050)), and represent the nominal orientation and location of 01024 the data. This method can also be used to represent "aligned" 01025 coordinates, which would typically result from some post-acquisition 01026 alignment of the volume to a standard orientation (e.g., the same 01027 subject on another day, or a rigid rotation to true anatomical 01028 orientation from the tilted position of the subject in the scanner). 01029 The formula for (x,y,z) in terms of header parameters and (i,j,k) is: 01030 01031 [ x ] [ R11 R12 R13 ] [ pixdim[1] * i ] [ qoffset_x ] 01032 [ y ] = [ R21 R22 R23 ] [ pixdim[2] * j ] + [ qoffset_y ] 01033 [ z ] [ R31 R32 R33 ] [ qfac * pixdim[3] * k ] [ qoffset_z ] 01034 01035 The qoffset_* shifts are in the NIFTI-1 header. Note that the center 01036 of the (i,j,k)=(0,0,0) voxel (first value in the dataset array) is 01037 just (x,y,z)=(qoffset_x,qoffset_y,qoffset_z). 01038 01039 The rotation matrix R is calculated from the quatern_* parameters. 01040 This calculation is described below. 01041 01042 The scaling factor qfac is either 1 or -1. The rotation matrix R 01043 defined by the quaternion parameters is "proper" (has determinant 1). 01044 This may not fit the needs of the data; for example, if the image 01045 grid is 01046 i increases from Left-to-Right 01047 j increases from Anterior-to-Posterior 01048 k increases from Inferior-to-Superior 01049 Then (i,j,k) is a left-handed triple. In this example, if qfac=1, 01050 the R matrix would have to be 01051 01052 [ 1 0 0 ] 01053 [ 0 -1 0 ] which is "improper" (determinant = -1). 01054 [ 0 0 1 ] 01055 01056 If we set qfac=-1, then the R matrix would be 01057 01058 [ 1 0 0 ] 01059 [ 0 -1 0 ] which is proper. 01060 [ 0 0 -1 ] 01061 01062 This R matrix is represented by quaternion [a,b,c,d] = [0,1,0,0] 01063 (which encodes a 180 degree rotation about the x-axis). 01064 01065 METHOD 3 (used when sform_code > 0): 01066 ----------------------------------- 01067 The (x,y,z) coordinates are given by a general affine transformation 01068 of the (i,j,k) indexes: 01069 01070 x = srow_x[0] * i + srow_x[1] * j + srow_x[2] * k + srow_x[3] 01071 y = srow_y[0] * i + srow_y[1] * j + srow_y[2] * k + srow_y[3] 01072 z = srow_z[0] * i + srow_z[1] * j + srow_z[2] * k + srow_z[3] 01073 01074 The srow_* vectors are in the NIFTI_1 header. Note that no use is 01075 made of pixdim[] in this method. 01076 01077 WHY 3 METHODS? 01078 -------------- 01079 Method 1 is provided only for backwards compatibility. The intention 01080 is that Method 2 (qform_code > 0) represents the nominal voxel locations 01081 as reported by the scanner, or as rotated to some fiducial orientation and 01082 location. Method 3, if present (sform_code > 0), is to be used to give 01083 the location of the voxels in some standard space. The sform_code 01084 indicates which standard space is present. Both methods 2 and 3 can be 01085 present, and be useful in different contexts (method 2 for displaying the 01086 data on its original grid; method 3 for displaying it on a standard grid). 01087 01088 In this scheme, a dataset would originally be set up so that the 01089 Method 2 coordinates represent what the scanner reported. Later, 01090 a registration to some standard space can be computed and inserted 01091 in the header. Image display software can use either transform, 01092 depending on its purposes and needs. 01093 01094 In Method 2, the origin of coordinates would generally be whatever 01095 the scanner origin is; for example, in MRI, (0,0,0) is the center 01096 of the gradient coil. 01097 01098 In Method 3, the origin of coordinates would depend on the value 01099 of sform_code; for example, for the Talairach coordinate system, 01100 (0,0,0) corresponds to the Anterior Commissure. 01101 01102 QUATERNION REPRESENTATION OF ROTATION MATRIX (METHOD 2) 01103 ------------------------------------------------------- 01104 The orientation of the (x,y,z) axes relative to the (i,j,k) axes 01105 in 3D space is specified using a unit quaternion [a,b,c,d], where 01106 a*a+b*b+c*c+d*d=1. The (b,c,d) values are all that is needed, since 01107 we require that a = sqrt(1.0-(b*b+c*c+d*d)) be nonnegative. The (b,c,d) 01108 values are stored in the (quatern_b,quatern_c,quatern_d) fields. 01109 01110 The quaternion representation is chosen for its compactness in 01111 representing rotations. The (proper) 3x3 rotation matrix that 01112 corresponds to [a,b,c,d] is 01113 01114 [ a*a+b*b-c*c-d*d 2*b*c-2*a*d 2*b*d+2*a*c ] 01115 R = [ 2*b*c+2*a*d a*a+c*c-b*b-d*d 2*c*d-2*a*b ] 01116 [ 2*b*d-2*a*c 2*c*d+2*a*b a*a+d*d-c*c-b*b ] 01117 01118 [ R11 R12 R13 ] 01119 = [ R21 R22 R23 ] 01120 [ R31 R32 R33 ] 01121 01122 If (p,q,r) is a unit 3-vector, then rotation of angle h about that 01123 direction is represented by the quaternion 01124 01125 [a,b,c,d] = [cos(h/2), p*sin(h/2), q*sin(h/2), r*sin(h/2)]. 01126 01127 Requiring a >= 0 is equivalent to requiring -Pi <= h <= Pi. (Note that 01128 [-a,-b,-c,-d] represents the same rotation as [a,b,c,d]; there are 2 01129 quaternions that can be used to represent a given rotation matrix R.) 01130 To rotate a 3-vector (x,y,z) using quaternions, we compute the 01131 quaternion product 01132 01133 [0,x',y',z'] = [a,b,c,d] * [0,x,y,z] * [a,-b,-c,-d] 01134 01135 which is equivalent to the matrix-vector multiply 01136 01137 [ x' ] [ x ] 01138 [ y' ] = R [ y ] (equivalence depends on a*a+b*b+c*c+d*d=1) 01139 [ z' ] [ z ] 01140 01141 Multiplication of 2 quaternions is defined by the following: 01142 01143 [a,b,c,d] = a*1 + b*I + c*J + d*K 01144 where 01145 I*I = J*J = K*K = -1 (I,J,K are square roots of -1) 01146 I*J = K J*K = I K*I = J 01147 J*I = -K K*J = -I I*K = -J (not commutative!) 01148 For example 01149 [a,b,0,0] * [0,0,0,1] = [0,0,-b,a] 01150 since this expands to 01151 (a+b*I)*(K) = (a*K+b*I*K) = (a*K-b*J). 01152 01153 The above formula shows how to go from quaternion (b,c,d) to 01154 rotation matrix and direction cosines. Conversely, given R, 01155 we can compute the fields for the NIFTI-1 header by 01156 01157 a = 0.5 * sqrt(1+R11+R22+R33) (not stored) 01158 b = 0.25 * (R32-R23) / a => quatern_b 01159 c = 0.25 * (R13-R31) / a => quatern_c 01160 d = 0.25 * (R21-R12) / a => quatern_d 01161 01162 If a=0 (a 180 degree rotation), alternative formulas are needed. 01163 See the nifti1_io.c function mat44_to_quatern() for an implementation 01164 of the various cases in converting R to [a,b,c,d]. 01165 01166 Note that R-transpose (= R-inverse) would lead to the quaternion 01167 [a,-b,-c,-d]. 01168 01169 The choice to specify the qoffset_x (etc.) values in the final 01170 coordinate system is partly to make it easy to convert DICOM images to 01171 this format. The DICOM attribute "Image Position (Patient)" (0020,0032) 01172 stores the (Xd,Yd,Zd) coordinates of the center of the first voxel. 01173 Here, (Xd,Yd,Zd) refer to DICOM coordinates, and Xd=-x, Yd=-y, Zd=z, 01174 where (x,y,z) refers to the NIFTI coordinate system discussed above. 01175 (i.e., DICOM +Xd is Left, +Yd is Posterior, +Zd is Superior, 01176 whereas +x is Right, +y is Anterior , +z is Superior. ) 01177 Thus, if the (0020,0032) DICOM attribute is extracted into (px,py,pz), then 01178 qoffset_x = -px qoffset_y = -py qoffset_z = pz 01179 is a reasonable setting when qform_code=NIFTI_XFORM_SCANNER_ANAT. 01180 01181 That is, DICOM's coordinate system is 180 degrees rotated about the z-axis 01182 from the neuroscience/NIFTI coordinate system. To transform between DICOM 01183 and NIFTI, you just have to negate the x- and y-coordinates. 01184 01185 The DICOM attribute (0020,0037) "Image Orientation (Patient)" gives the 01186 orientation of the x- and y-axes of the image data in terms of 2 3-vectors. 01187 The first vector is a unit vector along the x-axis, and the second is 01188 along the y-axis. If the (0020,0037) attribute is extracted into the 01189 value (xa,xb,xc,ya,yb,yc), then the first two columns of the R matrix 01190 would be 01191 [ -xa -ya ] 01192 [ -xb -yb ] 01193 [ xc yc ] 01194 The negations are because DICOM's x- and y-axes are reversed relative 01195 to NIFTI's. The third column of the R matrix gives the direction of 01196 displacement (relative to the subject) along the slice-wise direction. 01197 This orientation is not encoded in the DICOM standard in a simple way; 01198 DICOM is mostly concerned with 2D images. The third column of R will be 01199 either the cross-product of the first 2 columns or its negative. It is 01200 possible to infer the sign of the 3rd column by examining the coordinates 01201 in DICOM attribute (0020,0032) "Image Position (Patient)" for successive 01202 slices. However, this method occasionally fails for reasons that I 01203 (RW Cox) do not understand. 01204 -----------------------------------------------------------------------------*/ 01205 01206 /* [qs]form_code value: */ /* x,y,z coordinate system refers to: */ 01207 /*-----------------------*/ /*---------------------------------------*/ 01208 01215 #define NIFTI_XFORM_UNKNOWN 0 01216 01219 #define NIFTI_XFORM_SCANNER_ANAT 1 01220 01224 #define NIFTI_XFORM_ALIGNED_ANAT 2 01225 01229 #define NIFTI_XFORM_TALAIRACH 3 01230 01233 #define NIFTI_XFORM_MNI_152 4 01234 /* @} */ 01235 01236 /*---------------------------------------------------------------------------*/ 01237 /* UNITS OF SPATIAL AND TEMPORAL DIMENSIONS: 01238 ---------------------------------------- 01239 The codes below can be used in xyzt_units to indicate the units of pixdim. 01240 As noted earlier, dimensions 1,2,3 are for x,y,z; dimension 4 is for 01241 time (t). 01242 - If dim[4]=1 or dim[0] < 4, there is no time axis. 01243 - A single time series (no space) would be specified with 01244 - dim[0] = 4 (for scalar data) or dim[0] = 5 (for vector data) 01245 - dim[1] = dim[2] = dim[3] = 1 01246 - dim[4] = number of time points 01247 - pixdim[4] = time step 01248 - xyzt_units indicates units of pixdim[4] 01249 - dim[5] = number of values stored at each time point 01250 01251 Bits 0..2 of xyzt_units specify the units of pixdim[1..3] 01252 (e.g., spatial units are values 1..7). 01253 Bits 3..5 of xyzt_units specify the units of pixdim[4] 01254 (e.g., temporal units are multiples of 8). 01255 01256 This compression of 2 distinct concepts into 1 byte is due to the 01257 limited space available in the 348 byte ANALYZE 7.5 header. The 01258 macros XYZT_TO_SPACE and XYZT_TO_TIME can be used to mask off the 01259 undesired bits from the xyzt_units fields, leaving "pure" space 01260 and time codes. Inversely, the macro SPACE_TIME_TO_XYZT can be 01261 used to assemble a space code (0,1,2,...,7) with a time code 01262 (0,8,16,32,...,56) into the combined value for xyzt_units. 01263 01264 Note that codes are provided to indicate the "time" axis units are 01265 actually frequency in Hertz (_HZ), in part-per-million (_PPM) 01266 or in radians-per-second (_RADS). 01267 01268 The toffset field can be used to indicate a nonzero start point for 01269 the time axis. That is, time point #m is at t=toffset+m*pixdim[4] 01270 for m=0..dim[4]-1. 01271 -----------------------------------------------------------------------------*/ 01272 01279 #define NIFTI_UNITS_UNKNOWN 0 01280 01283 #define NIFTI_UNITS_METER 1 01284 01285 #define NIFTI_UNITS_MM 2 01286 01287 #define NIFTI_UNITS_MICRON 3 01288 01291 #define NIFTI_UNITS_SEC 8 01292 01293 #define NIFTI_UNITS_MSEC 16 01294 01295 #define NIFTI_UNITS_USEC 24 01296 01297 /*** These units are for spectral data: ***/ 01299 #define NIFTI_UNITS_HZ 32 01300 01301 #define NIFTI_UNITS_PPM 40 01302 01303 #define NIFTI_UNITS_RADS 48 01304 /* @} */ 01305 01306 #undef XYZT_TO_SPACE 01307 #undef XYZT_TO_TIME 01308 #define XYZT_TO_SPACE(xyzt) ( (xyzt) & 0x07 ) 01309 #define XYZT_TO_TIME(xyzt) ( (xyzt) & 0x38 ) 01310 01311 #undef SPACE_TIME_TO_XYZT 01312 #define SPACE_TIME_TO_XYZT(ss,tt) ( (((char)(ss)) & 0x07) \ 01313 | (((char)(tt)) & 0x38) ) 01314 01315 /*---------------------------------------------------------------------------*/ 01316 /* MRI-SPECIFIC SPATIAL AND TEMPORAL INFORMATION: 01317 --------------------------------------------- 01318 A few fields are provided to store some extra information 01319 that is sometimes important when storing the image data 01320 from an FMRI time series experiment. (After processing such 01321 data into statistical images, these fields are not likely 01322 to be useful.) 01323 01324 { freq_dim } = These fields encode which spatial dimension (1,2, or 3) 01325 { phase_dim } = corresponds to which acquisition dimension for MRI data. 01326 { slice_dim } = 01327 Examples: 01328 Rectangular scan multi-slice EPI: 01329 freq_dim = 1 phase_dim = 2 slice_dim = 3 (or some permutation) 01330 Spiral scan multi-slice EPI: 01331 freq_dim = phase_dim = 0 slice_dim = 3 01332 since the concepts of frequency- and phase-encoding directions 01333 don't apply to spiral scan 01334 01335 slice_duration = If this is positive, AND if slice_dim is nonzero, 01336 indicates the amount of time used to acquire 1 slice. 01337 slice_duration*dim[slice_dim] can be less than pixdim[4] 01338 with a clustered acquisition method, for example. 01339 01340 slice_code = If this is nonzero, AND if slice_dim is nonzero, AND 01341 if slice_duration is positive, indicates the timing 01342 pattern of the slice acquisition. The following codes 01343 are defined: 01344 NIFTI_SLICE_SEQ_INC == sequential increasing 01345 NIFTI_SLICE_SEQ_DEC == sequential decreasing 01346 NIFTI_SLICE_ALT_INC == alternating increasing 01347 NIFTI_SLICE_ALT_DEC == alternating decreasing 01348 NIFTI_SLICE_ALT_INC2 == alternating increasing #2 01349 NIFTI_SLICE_ALT_DEC2 == alternating decreasing #2 01350 { slice_start } = Indicates the start and end of the slice acquisition 01351 { slice_end } = pattern, when slice_code is nonzero. These values 01352 are present to allow for the possible addition of 01353 "padded" slices at either end of the volume, which 01354 don't fit into the slice timing pattern. If there 01355 are no padding slices, then slice_start=0 and 01356 slice_end=dim[slice_dim]-1 are the correct values. 01357 For these values to be meaningful, slice_start must 01358 be non-negative and slice_end must be greater than 01359 slice_start. Otherwise, they should be ignored. 01360 01361 The following table indicates the slice timing pattern, relative to 01362 time=0 for the first slice acquired, for some sample cases. Here, 01363 dim[slice_dim]=7 (there are 7 slices, labeled 0..6), slice_duration=0.1, 01364 and slice_start=1, slice_end=5 (1 padded slice on each end). 01365 01366 slice 01367 index SEQ_INC SEQ_DEC ALT_INC ALT_DEC ALT_INC2 ALT_DEC2 01368 6 : n/a n/a n/a n/a n/a n/a n/a = not applicable 01369 5 : 0.4 0.0 0.2 0.0 0.4 0.2 (slice time offset 01370 4 : 0.3 0.1 0.4 0.3 0.1 0.0 doesn't apply to 01371 3 : 0.2 0.2 0.1 0.1 0.3 0.3 slices outside 01372 2 : 0.1 0.3 0.3 0.4 0.0 0.1 the range 01373 1 : 0.0 0.4 0.0 0.2 0.2 0.4 slice_start .. 01374 0 : n/a n/a n/a n/a n/a n/a slice_end) 01375 01376 The SEQ slice_codes are sequential ordering (uncommon but not unknown), 01377 either increasing in slice number or decreasing (INC or DEC), as 01378 illustrated above. 01379 01380 The ALT slice codes are alternating ordering. The 'standard' way for 01381 these to operate (without the '2' on the end) is for the slice timing 01382 to start at the edge of the slice_start .. slice_end group (at slice_start 01383 for INC and at slice_end for DEC). For the 'ALT_*2' slice_codes, the 01384 slice timing instead starts at the first slice in from the edge (at 01385 slice_start+1 for INC2 and at slice_end-1 for DEC2). This latter 01386 acquisition scheme is found on some Siemens scanners. 01387 01388 The fields freq_dim, phase_dim, slice_dim are all squished into the single 01389 byte field dim_info (2 bits each, since the values for each field are 01390 limited to the range 0..3). This unpleasantness is due to lack of space 01391 in the 348 byte allowance. 01392 01393 The macros DIM_INFO_TO_FREQ_DIM, DIM_INFO_TO_PHASE_DIM, and 01394 DIM_INFO_TO_SLICE_DIM can be used to extract these values from the 01395 dim_info byte. 01396 01397 The macro FPS_INTO_DIM_INFO can be used to put these 3 values 01398 into the dim_info byte. 01399 -----------------------------------------------------------------------------*/ 01400 01401 #undef DIM_INFO_TO_FREQ_DIM 01402 #undef DIM_INFO_TO_PHASE_DIM 01403 #undef DIM_INFO_TO_SLICE_DIM 01404 01405 #define DIM_INFO_TO_FREQ_DIM(di) ( ((di) ) & 0x03 ) 01406 #define DIM_INFO_TO_PHASE_DIM(di) ( ((di) >> 2) & 0x03 ) 01407 #define DIM_INFO_TO_SLICE_DIM(di) ( ((di) >> 4) & 0x03 ) 01408 01409 #undef FPS_INTO_DIM_INFO 01410 #define FPS_INTO_DIM_INFO(fd,pd,sd) ( ( ( ((char)(fd)) & 0x03) ) | \ 01411 ( ( ((char)(pd)) & 0x03) << 2 ) | \ 01412 ( ( ((char)(sd)) & 0x03) << 4 ) ) 01413 01419 #define NIFTI_SLICE_UNKNOWN 0 01420 #define NIFTI_SLICE_SEQ_INC 1 01421 #define NIFTI_SLICE_SEQ_DEC 2 01422 #define NIFTI_SLICE_ALT_INC 3 01423 #define NIFTI_SLICE_ALT_DEC 4 01424 #define NIFTI_SLICE_ALT_INC2 5 /* 05 May 2005: RWCox */ 01425 #define NIFTI_SLICE_ALT_DEC2 6 /* 05 May 2005: RWCox */ 01426 /* @} */ 01427 01428 /*---------------------------------------------------------------------------*/ 01429 /* UNUSED FIELDS: 01430 ------------- 01431 Some of the ANALYZE 7.5 fields marked as ++UNUSED++ may need to be set 01432 to particular values for compatibility with other programs. The issue 01433 of interoperability of ANALYZE 7.5 files is a murky one -- not all 01434 programs require exactly the same set of fields. (Unobscuring this 01435 murkiness is a principal motivation behind NIFTI-1.) 01436 01437 Some of the fields that may need to be set for other (non-NIFTI aware) 01438 software to be happy are: 01439 01440 extents dbh.h says this should be 16384 01441 regular dbh.h says this should be the character 'r' 01442 glmin, } dbh.h says these values should be the min and max voxel 01443 glmax } values for the entire dataset 01444 01445 It is best to initialize ALL fields in the NIFTI-1 header to 0 01446 (e.g., with calloc()), then fill in what is needed. 01447 -----------------------------------------------------------------------------*/ 01448 01449 /*---------------------------------------------------------------------------*/ 01450 /* MISCELLANEOUS C MACROS 01451 -----------------------------------------------------------------------------*/ 01452 01453 /*.................*/ 01457 #define NIFTI_VERSION(h) \ 01458 ( ( (h).magic[0]=='n' && (h).magic[3]=='\0' && \ 01459 ( (h).magic[1]=='i' || (h).magic[1]=='+' ) && \ 01460 ( (h).magic[2]>='1' && (h).magic[2]<='9' ) ) \ 01461 ? (h).magic[2]-'0' : 0 ) 01462 01463 /*.................*/ 01468 #define NIFTI_ONEFILE(h) ( (h).magic[1] == '+' ) 01469 01470 /*.................*/ 01474 #define NIFTI_NEEDS_SWAP(h) ( (h).dim[0] < 0 || (h).dim[0] > 7 ) 01475 01476 /*.................*/ 01480 #define NIFTI_5TH_DIM(h) ( ((h).dim[0]>4 && (h).dim[5]>1) ? (h).dim[5] : 0 ) 01481 01482 /*****************************************************************************/ 01483 01484 /*=================*/ 01485 #ifdef __cplusplus 01486 } 01487 #endif 01488 /*=================*/ 01489 01490 #endif /* _NIFTI_HEADER_ */